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The debilitating, slow damage created by high levels of blood sugar (glucose) destroys everything from your blood vessels to your eyes, kidneys, and nerves over time due to oxidative stress (remember the free radicals or reactive oxygen species (ROS)?)

Schewe, H., Kreutzer, A., Schmidt, I., Schubert, C

Additionally, the excessive metabolism of iron can accelerate this process, ultimately leading to ferroptosis in RPECs (169)

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Han D, Fang Y, Tan X, Jiang H, Gong X, Wang X, Hong W, Tu J, Wei W

Cell surface interactions of Rhizobium bacteroids and other bacterial strains with symbiosomal and peribacteroid membrane components from pea nodules