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(Supplemental Tables S-1, S-2a, and S-3a)

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We showed that Mn treatment in rat-derived mesencephalic dopaminergic neuronal (N27) cells increases reactive oxygen species (ROS) production ( c release, caspase-3 activation, and DNA fragmentation

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These proteins included chitotriosidase-1, serum amyloid protein P, surfactant protein D, S100P, inter-alpha-trypsin inhibitor, annexin, glutathione- S -transferase, interleukin-1 receptor accessory protein, cystatin-5, caveolin, choline transport protein, Fc-gamma RII-a, (Fc-binding protein), interleukin 6 receptor, programmed cell death 1 ligand 2, and aquaporin-1