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10.1111/liv.15600 86 MaccioniL.GaoB.LeclercqS.PirlotB.HorsmansY.DE TimaryP.et al (2020)

Following 1.53 min baseline recording, two iterations of a 5 sec spot stimulation followed by an 810 min recording were imaged

In the in vitro study, the cytotoxicity of sertraline, fluoxetine, and citalopram were first assessed in MRP1- or MRP7-overexpressing cell lines, and the non-toxic concentrations were used in the following reversal studies

N-acetylcysteine (NAC) is the antidote and achieves maximum hepatoprotective effect when initiated within 8 to 10 hours of ingestion

This catastrophic failure of cellular energy production is a primary driver of post-exertional malaise (PEM), the defining symptom of ME/CFS and many cases of Long COVID, where even minor physical or cognitive exertion leads to a disproportionate and prolonged crash in functioning

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