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Macrophages are primarily derived from bone marrow-resident haematopoietic stem cells (112)

Similarly, cyclic hydrostatic pressure enhances the chondrogenic differentiation of BMSCs (Ogawa et al., 2009) in a dose- and time-dependent manner, and shows synergistic effects when co-cultured with nucleus pulposus cells ( In contrast, static loading generally produces negative effects

Glutathione synthetase in erythrocytes and/or cultured fibroblasts can be measured as described elsewhere [1]

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His plasma cysteine and plasma sulfate levels (measured by Great Smokies Lab) increased in the first 5 weeks from well below to almost into the bottom of the reference range

Furthermore, increased copper levels can increase reactive oxygen species (ROS) production and activate the NF-B signalling pathway, exacerbating inflammatory changes within the vascular wall and promoting atherosclerosis (25)