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doi: 10.1002/yea.1706 104 LuH.ChenH.TangX.YangQ.ZhangH.ChenY

Interestingly, LATS1/2 depletion was able to silence the expression of the Wnt target gene, MYC , even in the APC mutant intestinal cells, making it a good candidate for intestinal tumor therapy

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Individuals at risk of vitamin B12 deficiency include older adults, people with gastrointestinal disorders, those who have had gastrointestinal surgeries, individuals on a strict vegan diet, individuals who take metformin for blood sugar control, and people taking proton pump inhibitors for chronic heartburn

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As the pedigree depicted autosomal recessive inheritance, homozygous and compound heterozygous variants were preferred but heterozygous variants were not ignored