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1 H-MRS is a powerful technique, which in the past decades has been used in both pre-clinical and clinical studies and allows a non-invasive profiling of brain metabolites in a region-specific manner [60]

Even more concerning are findings that MASLD, as an independent factor, increases the risk of certain extrahepatic tumors

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Therefore, these results demonstrated that decreased invasion might be responsible for the decreased tumorigenicity found in late passage

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Moreover, STRs have been shown elsewhere to affect gene expression cumulatively and indirectly by altering the binding affinity of neighbouring TFBS for TFs [36]