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Methods This comprehensive narrative review was conducted through a systematic literature search to identify relevant preclinical studies, clinical trials, and review articles on CAR-T therapy for neuroendocrine neoplasms

Andrographolide activates Keap1/Nrf2/ARE/HO-1 pathway in HT22 cells and suppresses microglial activation by Abeta42 through Nrf2-related inflammatory response

Tumor necrosis factor (TNF)- and IL-6 levels in BALF were determined using the appropriate mouse ELISA kits (Mouse TNF- ELISA MAX Deluxe Set and Mouse IL-6 ELISA MAX Deluxe Set, BioLegend, San Diego, CA, United States)

However, current analytical methods often require tedious chemical derivatization, lack adequate retention and selectivity for highly polar analytes, or suffer from severe matrix effects when profiling the broader metabolic pathway

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During micelle formation, the hydrophilic polar groups form the outer layer, while the hydrophobic polar groups aggregate to form the core of the micelle, which can effectively carry hydrophobic drugs, improve the solubility of molecules, and prolong the circulation time of drugs in the body [62]