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We summarize the effects of UA on immune cell-associated inflammatory responses from recent studies and debate the crucial role of immune cells in HUA and its associated disorders

Efficacy outcomes evaluated in pruritus responders (defined as patients achieving a 1-point decrease in ObsRO scratching score from baseline to weeks 2124) were change from baseline in ObsRO scratching score, serum bile acids, ObsRO sleep parameters, and caregiver-reported Pediatric Quality of Life Inventory (PedsQL) scores

GHK-Cu is a cosmetic peptide known for supporting skin and scalp appearance, not a drug or FDA-approved treatment for hair loss

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Physicians should also aggressively diagnose and treat suspected infections with antibiotics (Ferri 2013a)