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Recent studies confirmed that daratumumab lacks the ability to induce apoptosis in the absence of crosslinking agents, though the contribution of direct cell death to overall anti-CD38 killing of MM cells in patients remains to be fully characterized [28]

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1A) showed that with PLB treatment, the pathological structure of ovarian tissue showed significant improvement, including more normal follicular development and a reduction in cysts, indicating its protective effect on ovarian morphology

[DOI] [PubMed] [Google Scholar] Lanphear BP, Hornung R, Khoury J, Yolton K, Baghurst P, Bellinger DC, Canfield RL, Dietrich KN, Bornschein R, Greene T, Rothenberg SJ, Needleman HL, Schnaas L, Wasserman G, Graziano J, Roberts R

Gene structure and conserved motif analysis demonstrated that AsGST genes within the same subfamily shares similarities in the number and positioning of exons and introns, as well as in motif composition, suggesting that these genes may perform analogous biological functions in A