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Neuroinflammation and mitochondrial dysfunction in Parkinsons disease: connecting neuroimaging with pathophysiology

Its cumulative effect may damage the kidneys or even cause neurological effects

The documented considerations include mild water retention (a class effect of raising GH), injection-site reactions, occasional headache or lightheadedness, and most importantly for long-term thinking IGF-1 and sustained-GH-elevation considerations, which are why cycling with breaks is favored over indefinite use

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The Mayo Clinic also emphasizes practical steps for day-to-day relief