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Parallel studies have shown that nuclear translocation of ACSS2 in hippocampal neurons was key to allowing histone acetylation locally at neuronal genes, a critical switch to drive long-term spatial memory (Mews et al., 2017)

3.1.4 Lipid homeostasis The mechanism of ferroptosis is highly regulated by cellular lipid and its metabolism

Limitationa and perspectives Targeting ferroptosis appears to have a favorable impact on the clinical treatment of multiple human diseases

doi:10.1371/journal.pone.0088630 Morris D, Guerra C, Khurasany M, Guilford F, Saviola B, Huang Y, Venketaraman V (2013) Glutathione supplementation improves macrophage functions in HIV