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J Neurosci 29:38433851 Levano S, Bodmer D (2015) Loss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors

Both pathways utilize polyunsaturated fatty acid (PUFA)-containing phospholipids (PLs) as substrates

Consuming adequate cysteine and NAC is important for a variety of health reasons including replenishing the most powerful antioxidant in your body, glutathione

However, researchers may consider starting at a significantly lower dose of intranasal PT-141, and titrating up based on the subjects response and tolerability