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61 A meta-analysis of data from eight randomized controlled trials found a combination of omega-3 fatty acids plus statin therapy was more effective than statin therapy alone for stabilizing and promoting regression of atherosclerotic plaques in the coronary arteries, possibly reducing the risk of arterial thromboembolism

In the lamina propria, some GIP glutamines are deamidated to glutamate by transglutaminase 2 (TG2) (Zhuang and Khosla, 2020) and subsequently bind to antigen-presenting cells (APCs)dendritic cells, macrophages, and B cells (Wei et al, 2020)previously activated by pro-inflammatory cytokines such as interleukin (IL)-15 and type-1 interferons (IFNs)

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It has been shown to stimulate the production of type II collagen, which is a key component of cartilage tissue, and to inhibit the production of enzymes that can break down cartilage.Furthermore, AOD-9604 has been shown to be safe and well-tolerated in clinical trials

Mild cases may improve within a few weeks with rest and treatment, while more severe cases can take several months

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