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For clinical planning, we rank peptides according to angiogenic potency and safety profile to inform dosing and combination therapy decisions

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High yields were achieved by using 3- and 4-fluorobenzaldehyde, salicylaldehyde, and 4-hydroxybenzaldehyde in combination with methyl 3-aminocrotonate and 5-methyl furfural, while the lowest yield was attained with 3-indole-carboxaldehyde (Scheme 37)

And I was like, no, it's not easy

Compared to the negative control group of mice, WBC counts in ETX-infected mice were elevated 300%

Simons M, Gordon E, Claesson-Welsh L