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Guttiferone K isolated from Yunnan Baiyao was able to inhibit the downstream NF-B and Akt/mTOR signaling pathways via the TLR/IRAK-1 pathway, thereby significantly inducing autophagy and suppressing MTB-induced inflammatory responses in macrophages (113)

Moreover, neuron-specific ablation of GPX4 in the forebrain (cerebral cortex and hippocampus) was associated with an increase in markers associated with ferroptosis including increased lipid peroxidation, extracellular-regulated kinase (ERK) 4 and neuroinflammation (Hambright et al., During ferroptosis, cytosolic ferritin may undergo lysosomal breakdown (ferritinophagy) to further contribute to LIPferritinophagy appears to augment cysteine deficiency-induced ferroptosis (Gao et al., via hyperpolarized mitochondrial membrane potential (Gao et al., 2007

10.1034/j.1600-079x.2003.01897.x 420 ZhuZ.LiS.YinX.SunK.SongJ.RenW.et al (2024)

Physicochemical properties and cytotoxicity of iron oxide nanoparticles

PeptiSleep: Natural Sleep Optimization PeptiSleep, derived from rice bran protein, represents the worlds first AI-discovered plant-based peptide designed to enhance all stages of sleep

Clinical Nutrition 35(4):842851