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However, to elucidate the molecular mechanism of HMOX1 activity would help to understand those effects and to the development of new potential therapies for IBD (Figure 1B)

EP4 signalling also reduced Rap1 GAP expression and promoted RCC invasion

This is to: a) rule out underlying issues

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The receiver operating characteristic curve was plotted, and the area under the receiver operating characteristic curve (AUC) and the cut-off value were calculated to evaluate the models predictive value for cirrhosis occurrence