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Toxicology international 20, 160 (2013)

& Dehpour, A

Clinical trials are an essential step to finding revolutionary medical treatments and medications to treat chronic diseases like cancer, diabetes, and neurological conditions

When the neurotoxicity values of the compounds were examined, oleocanthal: 0.729, oleacein: 0.255, luteolin: 0.212, tyrosol: 0.204, ezetimibe: 0.969, and bempedoic acid: 0.006 were determined

Results demonstrated that LMWF treatment in bleomycin-induced pulmonary fibrosis mice decreased TGF-, TNF-, and IL-6 expression in lung tissue, mirroring the effects of nintedanib in reducing inflammatory cytokine accumulation

Similarly, treatment of 7 with NaBH 4 resulted in the ring-opening and reduced mono-adducts 18 , which was stable and not active toward BME anymore (Fig