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Vasanthakumar and Ahmed, Cancer Commun

60, 61 CTP1C expression displays an inverse correlation with the activation of mTOR pathway and attenuates tumor sensitivity to rapamycin (a mTOR inhibitor), 18 which suggests that the CPTIC-involved pathway parallels to mTOR-enhanced glycolysis

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At the indicated tissue harvest time, mice were anesthetized with an 87.5 mg/kg ketamine, 12.5 mg/kg xylazine mixture, and then transcardially perfused with ice-cold 0.1 m PBS

The bell-curve dose-response means starting low and titrating to the individual response is more important than with other peptides

This is a particularly interesting possibility given that diet might be a significant contributing factor to ASD risk associated with TMLHE mutations