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By blocking NNMT, it shifts intracellular NAD+ and S-adenosylmethionine (SAM) levels, two cofactors tied to energy metabolism, redox balance, and gene regulation in laboratory models

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Dominique Bridon holds a Master of Science, Chemical Engineering and Polymer Sciences from Ecole Nationale Suprieure de Chimie and a PhD in Organic Chemistry from the University of Paris XI, ICSN, Orsay, France with Nobel Laureate Sir Derek H

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The NAD + -consuming enzyme SARM1, which can sense an elevated NMN/NAD + ratio, is activated and further degrades NAD + , ultimately triggering a programmed axonal self-destructive program [134]