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But now Northwestern Medicine scientists report results of the first in-human clinical trial in which they used a novel, skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate large, critical regions of the human brain to deliver chemotherapy that was injected intravenously

Taken together, these findings indicate a potential relationship between protein oxidation, Ca 2+ regulation, and protein aggregation in ALS (Fig

Availability of data and materials N/A Abbreviations DMARDS: Disease modifying antirheumatic drugs MCV: Mean corpuscular volume MTX: Methotrexate RA: Rheumatoid arthritis References Romo VC, Lima A, Bernardes M, Canho H, Fonseca JE

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Importance of selenium and selenoprotein for brain function: From antioxidant protection to neuronal signalling