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MCT1 ablation in Schwann cells impairs glycolytic and mitochondrial functions, depletes the nerve of critical lipids, especially sphingomyelins, diacylglycerides, and triacylglycerides, and results in hypomyelination (Jha et al., 2020b)

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It is plausible to postulate that the first and second GSH molecule should interact during the reductive half-reaction of the dithiol mechanism with the 1st and 2nd glutathione-interaction site, respectively

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