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However, the levels of NADP + and NADPH in fresh and frozen blood differ

Clin Pharmacokinet 51:553572 Rau TF, Lu Q, Sharma S, Sun X, Leary G, Beckman ML, Hou Y, Wainwright MS, Kavanaugh M, Poulsen DJ, Black SM (2012) Oxygen glucose deprivation in rat hippocampal slice cultures results in alterations in carnitine homeostasis and mitochondrial dysfunction

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8 This was the first trial in patients with a first acute demyelinating event (now, clinically isolated syndrome) to show efficacy in delaying time-to-clinically definite MS and was recognized as a significant medical advance as it introduced the concept of early treatment and led to revisions in diagnostic criteria for MS