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Before human translation, essential parameters to define: optimal dosing, infusion/administration route, frequency, biomarkers to monitor (senescent cell burden, inflammatory cytokines, organ function), long-term follow-up for adverse outcomes (especially tumour risk)

Application of natural products in inducing ferroptosis in tumor cells The active ingredients of natural products originating from the plant kingdom mainly include flavonoids, alkaloids, polysaccharides, volatile oils, quinones, terpenoids, lignans, coumarins, saponins, cardiac glycosides, phenolic acids, amino acids and enzymes

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Microarray and RNA-sequencing studies have mapped its regulatory effect across approximately 4,000 human genes, including upregulation of VEGF, BDNF, and BMP-2 growth factors central to vascular, neural, and bone remodeling respectively

A previous study have identified bacterial markers obtained from Campylobacter concisus capable of indicate disease activity in CD [40]

Short-term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus