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Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors 10 days of MCQ! Day 3: Acetaminophen Overdose Answer: C N acetylcysteine (NAC) NAC is the antidote for acetaminophen overdose. It works by replenishing hepatic glutathione stores, which are rapidly depleted Mechanism of acetaminophen toxicity providing a summary of pathways Download Scientific Diagram Acetaminophen Toxicity: OPPOSITE EFFECTS OF TWO FORMS OF GLUTATHIONE PEROXIDASE ScienceDirect What substance depletion causes hepatic necrosis from acetaminophen overdose ? A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010
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