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Melatonin shows receptor-mediated immunomodulatory effects in the immune system [40] and reduces telomerase activity [41]

Intriguingly, BVR-A-related unresponsiveness of insulin signaling was associated with the aberrant regulation of downstream pathways such as the mTOR/autophagy axis (412)

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Figure 6 ATF4 May Regulate Asn Metabolism by Promoting ASNS Expression in GC To explore the clinical correlation between ATF4 and ASNS expressions, the level of ASNS was also evaluated in the same batch of tissue array ( Figure 7A )

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