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doi: 10.1111/acel.13289 119 ShenY.WangM.LiS.YangJ

It enhances growth hormone receptor expression and several pathways involved in cell growth and angiogenesis, and increases nitric oxide production by upregulating nitric oxide synthase (NOS) gene and protein expression

Similar protective effects with folinic acid supplementation were observed in fly and cellular model of AD including differentiated SH-SY5Y neuroblastoma cells treated with A142 oligomers and SH-SY5Y cells stably expressing APP with the Swedish mutation (APPswe) [123]