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After completion of the reaction, the mixture was then acidified with 10% AcOH in water (22.5 mL) and extracted with Et 2 O (5) to remove the MPAA

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Luiz-Ferreira, et al ., Scientific World Journal , doi: 10.1100/2012/327071 (2012)

Abbreviations AChE: Acetylcholinesterase Bti : Bacillus thuringiensis israelensis CHC: Cuticular hydrocarbon CPR: NADPH-cytochrome P450 reductase CYP: Cytochrome P450 DDT: Dichlorodiphenyltrichlorethane F: Phenylalanine GABA: -Aminobutyric acid GST: Glutathione S -transferases H: Histidine kdr : Knockdown resistance L: Leucine LLINs: Long-lasting insecticide nets PBA1c: 3-Phenoxybenzyl alcohol PBA1d: 3-Phenoxybenzaldehyde PBAcid: 3-Phenoxybenzoic acid RDL : Resistance to dieldrin gene S: Serine Vssc: Voltage-sensitive sodium channel References World Health Organization

This signaling cascade within the AP and the nucleus of the solitary tract (NTS) is believed to be the primary mechanism for inducing feelings of satiety and reducing food intake

A 9 mL sample of P