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TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis

For brain protection, in an animal model of Parkinsons disease, spermidine was shown to dose dependently attenuate striatal pro-inflammatory cytokine levels (TNF-, IL-1, IL-6) and to restore striatal neurochemistry (the level of catecholamines: dopamine, serotonin, nor-epinephrine and their metabolites

Lin ZY, Wu CC, Chuang YH, Chuang WL

Although the effect of some ER-phagy pathways on sensory neuropathies suggests the importance of this process in the peripheral nervous system, it is difficult to know how important loss of this selective autophagy subtype is for the genesis of neurodegenerative diseases of the central nervous system

Yasir M, Ali A, Ahmad I, Khan N, Ashraf M (2021) Effect of herbal formulation Sharbat Ahmad Shahi on serum BDNF level in mild to moderate cases of depressive disorder

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