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In simple terms, NAC fuels the system, while Glutathione does the cleanup

Klein BE, Klein R, Moss SE Am J Ophthalmol

Notably, dynamic transitions between PCD forms may be regulated by molecules such as p53, Beclin-1, and GPX4

I., Ikeda, T

Aberrant expression of E3 ubiquitin ligases is closely associated with ferroptosis in musculoskeletal diseases (89), with PD-1 playing a regulatory role in this context (90)