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If you get a B12 injection and it stings, that means it's not just B12

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Metabolic regulation of ATP breakdown and of adenosine production in rat brain extracts

The body stores Vitamin B12 readily, so maintenance may not be necessary or requested by patients for several months at a time

Glutathione inhibits tyrosinase, the enzyme that produces melanin

However, when investigating acute responses, dose-response relationships with exacting precision, or aiming for maximal therapeutic effect, the injectable form clearly holds an advantage