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This study showed an 8 times increase in the mean cobalamin concentration sustained 1 week following the final dose (Slot et al., 1997)

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However, individuals with absorption disorders may require significantly higher doses to achieve therapeutic levels

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It is what your body uses to help create energy, which is one of the reasons people feel more energized when they take B12

This allows oral megadoses (e.g., 1,000 g or more daily) to raise serum B levels even in individuals with pernicious anemia or low stomach acid