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doi: 10.1002/ijc.33781 11 DeBerardinisRJVousdenKHChandelNS

K.HamurcuM.BresticM.TopalA.GezginS

This reduces the ability of cytotoxic T cells to aid the virus in eluding the hosts defenses

The substitution of the amino acid (His to Arg) may alter the charged amino acid configuration, which could affect the enzyme activity more than neutral or hydrophobic amino acids (93)