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The development of ML-based HDIs prediction models requires two types of information: biological (e.g., synergy datasets from herb-drug combination matrices, gene expression, microRNA expression, and proteome) and chemical (e.g., chemical fingerprints and molecular descriptors of herbal products) [154]

Lumbar spinal stenosis (LSS) can result in irreversible nerve damage and dysfunction, primarily characterized by hypertrophy and fibrosis of the ligamentum flavum (LF)

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The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias