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Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals

Removing pyruvate in the media prevents the recycling of NADH into NAD + by the cytosolic LDH enzyme, forcing mitochondrial redox shuttle systems to support cytosolic redox balance 18

Panday et al., 2015)

fermentum ME-3 was isolated in 1995 at the University of Tartu, Estonia, from a healthy one year old child

The pharmacologic inhibition of the xc antioxidant system improves the antitumor efficacy of COX inhibitors in the in vivo model of 3-MCA tumorigenesis