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More recently, after the advent of gene technology and the possibility of overexpressing recombinant proteins in a host cell of choice, the concept of the Affinity Tag emerged

Immunity 40, 4050

Saunders/Elsevier

Some users employ a combination approach

Spatial immune hubs defined by conserved activated dendritic cells are remodeled by immunotherapy

For example, miR-30a inhibits autophagy by targeting BECN1 , thereby repressing autophagosome formation in cancer cells, 332 whereas miR-376b suppresses starvation- and rapamycin-induced autophagy through coordinated repression of ATG4C and BECN1