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doi: 10.1016/j.euroneuro.2008.08.001 99 BoyleMPBrewerJAFunatsuMWozniakDFTsienJZIzumiYet al

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This system involves enzymes such as CPTI, CACT and CPTII, and its activity can vary with fasting, exercise or carbohydrate availability, so simplistic interpretations should be avoided

There has to be a subjective interpretation component, because we are all different in terms of our pain threshold