chac1 glutathione TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme The CHAC1-inhibited Notch3 pathway is

The CHAC1 inhibited Notch3 pathway is involved in temozolomide induced glioma cytotoxicity ScienceDirect Frontiers The strategic breakdown: CHAC enzymes as regulators of glutathione homeostasis and disease implications BACH1CHAC1Glutathione Axis Aggravates Myocardial IschemiaReperfusion Injury by Enhancing Ferroptosis and Oxidative Stress CHAC2 is essential for self renewal and glutathione maintenance in human embryonic stem cells ScienceDirect Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element ScienceDirect

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