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Indeed, the sensitivity of different cancer cells to GPX4 inhibitors is highly variable, and some are unaffected by GPX4 (48)

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The organoids were incubated with dispase at 37 C for 30 min, after which they were washed twice with cold DMEM/F12 and collected by centrifugation (5 min, 4 C, 300 g )

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These are complementary mechanisms, though combination effects have not been studied

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