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The details of the multistep mechanism postulated for the reaction and the structural motifs of the several enzymes, which have been thoroughly investigated, cannot be described in detail

Astrocytes in culture produce anandamide and other acylethanolamides

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There is no obvious similarity in chemical structure among all of these substances, but they have in common the ability to stimulate the pentose phosphate pathway in red blood cells, which must mean that they are able to oxidize NADPH directly or indirectly

The biodistribution of Cy5-labeled SP and Cy5-labeled SP@M was then tested by in vivo imaging measurement of fluorescence intensity using a Caliper IVIS Lumina III In Vivo Imaging System (Perkin Elmer, USA) at specific time points (0.5, 6, and 24 h post-injection) ( n = 3 in each group)