Extracellular self-DNA has been associated with multiorgan failure after severe trauma (6670), including sepsis-like systemic inflammation (71), sepsis (72), can lead to myocarditis (7376) or lung inflammation (77), facilitates the reactivation of latent virus infections, including Herpes Simplex Virus, Varicella Zoster Virus, or HIV-1, and favours the development of autoimmune diseases such as systemic lupus erythematosus (SLE) and psoriasis (67, 76, 7886)
Altered intestinal microbiota-host mitochondria crosstalk in new onset Crohns disease
It adheres to and enriches in the colonic mucosa-associated microbiota (MAM), promoting colorectal cancer (CRC) progression (Navarro-Snchez et al., 2025)
Labeled peptides were combined, dried in a vacuum concentrator, and stored at -80 C
000651, Jackson Laboratory) were subcutaneously inoculated with 2 10 6 viable murine colon-26 cells (C26, provided by the Kepecs Lab, derived from the National Institutes of Health National Cancer Institute Division of Cancer Treatment and Diagnosis Tumor Repository) over the left flank as previously reported 56 , with age-matched controls receiving no inoculation
LCFAs therefore typically remain complexed with fatty-acid-binding proteins (FABPs), a family of small cytosolic lipid chaperones that bind FAs and other hydrophobic ligands