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The proteins extracted from Ni-NTA resin were subjected to SDS-PAGE on 415% Mini-PROTEAN TGX Precast Protein Gels (Bio-Rad, Hercules, CA, USA)

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While CBP/p300 is a well-validated direct interaction partner of NRF2 with prominent functions at enhancers, we report that this interaction is not required for NRF2-dependent NSCLC cell growth, indicating that NRF2 can sustain sufficient transcriptional activity in the absence of CBP/p300 coactivation

Interestingly Hua Han et al., recently have reported many synthesized derivatives from picroside-II and demonstrated the hepatoprotective activity of the derivatives evaluated on SMMC-7721 cells [84]

The largest longitudinal study on multi-year supplementation remains limited

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