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Furthermore, comprehensive pharmacokinetic analyses should be conducted in conjunction with pharmacodynamic data to establish a clear dose-response relationship

Chin J Cancer Res 33(3):308322

Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 delta Inhibitors

LORI BLUVAS M.D

(2024) demonstrated in vitro and in vivo in gemcitabine-resistant cholangiocarcinoma (a biliary cancer model) that CBD induced ROS production (measured by DCFH-DA), ER stress (upregulating CHOP and ATF4), and apoptosis, significantly inhibiting tumor growth in xenografts (Pongking et al

Only cells annotated as epithelial in the original work were considered