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Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy

2022;120(2):e80e84

Addition of ROS-Glo Detection Solution converts the precursor to luciferin and provides Ultra-Glo Recombinant Luciferase to produce light signal that is proportional to the level of HO present in the sample

Because TG2 activity is highly associated with cellular redox status and alterations in the bidirectional flux of cellular thiol modulate TG2 activity, regulation of thiol flux in cells probably affects the TG2-mediated aggregation of the GST tag and its interaction with cellular proteins