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37,38 Sympathetic signaling activates the hypothalamic-pituitary-adrenal (HPA) axis, a network that connects the nervous system to the adrenal glands and controls their release of the bodys primary stress hormone, cortisol

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Data from an additional batch of female MyRF / ( n = 7) and MyRF +/ ( n = 6) mice tested in the same MWM but trained for 9 d rather than 7 d did show a significant group difference in the percentage of time spent in the target quadrant during the 28 d probe test (Students t test: t = 3.32, df = 11, p = 0.006