does l-carnitine cause kidney stones History of L-carnitine: Implications for renal disease The Role of L-Carnitine in

Both primary genetic and acquired causes of the symptom have been described

Naturally synthesised by the body from two essential amino acids L-lysine and L-methionine, it plays an important role in weight loss

It contains Astaxanthin, Coenzyme Q10, L-Carnitine, Lycopene and Omega-3 fatty acids

R471C has been shown to localise to the membrane and has ~15% activity of wildtype OCTN2 in CHO cells, which is consistent with the observed reduction in currents for R471A, meanwhile Y358N in CHO cells has ~8% activity, though localisation data for Y358N is unavailable 11,50

In urinary metabolomics Dong et al

If no guidance is available, it is safer to attempt a GDR over weeks to months to discontinue rather than abruptly discontinuing