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D50.1 is underused

Lipid peroxidation, the executioner of ferroptosis, holds an undeniable role in the pathogenesis of BD

Additionally, GLPs lower plasma nitric oxide (NO) levels by inhibiting the mRNA expression of inducible nitric oxide synthase (iNOS), thereby alleviating oxidative damage and safeguarding pancreatic cells (Xie et al., 2020)

This dysbiosis may, in turn, disrupt intestinal immunity and homeostasis, contributing to systemic inflammation and perpetuating a harmful feedback loop