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DOX is responsible for this filtration barrier damage [5, 6]

Inactive pro-HGF was activated by uPA in the ECM (Shimizu et al., 2001)

A., Mellin, J

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HGF-induced activation of c-MET induced PI3K-dependent phosphorylation of PKB/AKT and its substrates GSK3 and FOXO3a, contributing to its anti-apoptotic function [28]