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Availability: InStock
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46 Mechanistically, the transcription factor Hes1 regulated by Notch signaling decreased the expression of PGC-1 by binding to its promoter

MBio 7:e02210e02215

Feb 2015;31(2):177-83

Stimulation of mitochondrial biogenesis is important to improve and stabilize synaptic transmission, for which about 30% of the energy in the human brain is spent (69)

There were mortality reductions from replacing 3% of energy with plant protein for these animal products: Processed red meat: ~34% Eggs: ~19% Unprocessed red meat: ~12% Dairy: ~8% Fish: ~6% Poultry: ~6 These are incremental estimates within typical intake ranges and dont reflect decreases to zero animal protein

Diets high in long-chain saturated fatty acids, typical of the Western diet, can increase ceramide production, while diets rich in unsaturated fats, such as the Mediterranean diet, can reduce ceramide levels