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To address these limitations, we propose the use of an Actor-Network Theory (ANT) perspective

It is best understood as a short-term pain-relief option that may be used while the provider evaluates the larger cause of symptoms

Nitric Oxide System Effects Nitric oxide serves as a signaling molecule throughout the body, influencing blood flow, cellular communication, and tissue repair

Short-term side effects include flushing (related to vasodilation), nausea (mitigated by maintaining appropriate hydration status), brief headache, or dizziness/lightheadedness

In the 2 largest cohorts, encompassing 61 of 64 patients, sirolimus use was reported as monotherapy without corticosteroids, providing a similar ORR of 88.7%

This data proves invaluable for identifying patterns and making adjustments