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Some drugs and chemicals, however, are predictably injurious for all G6PD-deficient subjects, 3 , 30 and these agents are listed in Table 28.2

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Sample Collection Serum: Allow samples to clot for 1 hour at room temperature or overnight at 28C before centrifugation at 1,000g for 20 minutes at 28C

Coactivator-associated arginine methyltransferase 1 (CARM1, also known as PRMT4) enhances cardiomyocyte sensitivity to ferroptosis by interacting with NFE2L2 (also known as NRF2) and promoting its methylation, which limits the transcriptional activity of NFE2L2 on GPX4 58

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